Free Vendor Technical Workshops

 

Monday Free Vendor Technical Workshops

pre-register at sponsor's booth to attend

 

Monday, July 30, 2018 @ 12:25-1:25 PM

Extend Your Application Reach with the New PrimeLC and SFC Solutions

Sponsored by Agilent Technologies

Location: Thurgood Marshall Ballroom North (Mezzanine Level)

Speakers: Martin Greiner, Marketing Manager Core LC and Daniel Kutscher, R&D, Agilent Technologies

The Agilent 1260 Infinity II PrimeLC is the newest family member of the InfinityLab LC series. High-pressure-mixing binary pump-like performance, automated solvent blending and seamless method transfer capability (ISET), representing the most capable LC. Discover the obvious choice paired with the Agilent Ultivo Triple Quadrupole. The Agilent InfinityLab SFC Solution provides the most powerful instrumentation available extending your application reach in multiple analysis types. This novel tool combines feed injection for larger injection volumes with ultra-fast separation for answers to challenging chiral and achiral separations. The Agilent InfinityLab SFC solution reduces toxic solvent use, making your lab greener.    

Monday, July 30, 2018 @ 12:25-1:25 PM

Effectively Supporting Synthetic Chemistry for Pharmaceutical and Academic Research

Sponsored by Thermo Fisher Scientific

Location: Madison Room (Mezzanine Level)

Speaker: Dr. Frank Steiner, Senior Manager, Application Development & Scientific Advisor, Thermo Fisher Scientific, Germering, Germany

Monitoring the synthesis of small or larger molecules is a key activity in pharmaceutical but also academic research. The investigation of new structural entities and compounds often requires re-creation of the characterized novel structures to conduct further general research or identify therapeutic properties. This workshop will showcase our comprehensive new workflow solution discussing not only fast mass confirmation, but also how to produce better mass balances of unknown impurities and non-chromophores. In addition, we discuss advanced system configurations multiplying detection options as well as productivity of multi-detector UHPLC setups.    

Monday, July 30, 2018 @ 12:25-1:25 PM

Perfect Fit in Pharmaceutical Drug Development – Best Solutions for Small and Large Molecules

Sponsored by MilliporeSigma

Location: Thurgood Marshall Ballroom West (Mezzanine Level)

Speakers: Jason Wrigley, MilliporeSigma, and Petra Lewits, Merck KGaA

HPLC is the preferred method for determination of pharmaceutical drugs, degradations, impurity profiling, and for analytical characterization during drug development. HPLC allows for the development of robust and reliable analytical methods with desired sensitivity and selectivity while also meeting cost effective requirements in a laboratory. It is therefore important to use the right column for small and large molecules depending on individual needs. Different column technologies and selectivities are available for impurity profiling and QC of APIs. This seminar will cover the best solutions for separation of small and large molecules in the pharmaceutical workflow.   

 

Tuesday Free Vendor Technical Workshops

pre-register at sponsor's booth to attend


Tuesday, July 31, 2018 @ 12:25-1:25 PM

Simple Approaches to Charge Variant Analysis

Sponsored by Thermo Fisher Scientific

Location: Thurgood Marshall Ballroom West (Mezzanine Level)

Speaker: Jonathan Bones, Principal Investigator, NIBRT Characterization and Comparability Laboratory, NIBRT

The characterization of monoclonal antibodies (mAbs) during biopharmaceutical development involves the identification, monitoring, and analysis of charge variants. Antibodies can exhibit changes in charge heterogeneity during production and purification caused by amino acid substitutions, glycosylation, and other post-translational or chemical modifications. Not only can these changes impact stability and activity, they can also cause adverse immunological reactions. Identification of charge variants in development, and their monitoring throughout manufacturing is therefore critical. In this presentation the use of ion exchange and reverse phase approaches is discussed along with enabling technologies that simplify analysis.    

Tuesday, July 31, 2018 @ 12:25-1:25 PM

Maximizing Sensitivity without Jeopardizing Ruggedness and Reliability 

Sponsored by Shimadzu Scientific Instruments

Location: Madison Room (Mezzanine Level)

In the ever-changing field of liquid chromatography, micro-LC could bring many desired advantages such as sensitivity boost, sample and solvents saving, expanded dynamic range of quantitation, and minimized matrix effects. Then why is it not widely used in routine laboratories? In this workshop, we will investigate the creation of a product that is developed around the unique physics of the micro-LC/MSMS technique. In addition, we will share how the product can resolve the challenges in foods and nutraceutical/pharmaceutical chemistry, without jeopardizing productivity and robustness.    

Tuesday, July 31, 2018 @ 12:25-1:25 PM

2DLC - A “Swiss Army Knife” to Solve Chromatographic Challenges?

Sponsored by Agilent Technologies

Location: Thurgood Marshall Ballroom North (Mezzanine Level)

Speakers: Ulrich Eberhardinger, Product Manager Agilent Technologies and an invited speaker

Do you have doubts on the purity of your analytes, even after performing modern HPLC? Lack of chromatographic resolution, preventing stable and robust quantitative results for your analytes? Still doing manual sample preparation prior to your chromatography to obtain reasonable peak shapes? These chromatographic challenges can be addressed by applying state-of-the art multidimensional HPLC without the necessity of being an expert in the technique. Join us for a discussion of the latest solutions for 2DLC in combination with real-life industrial applications highlighting the benefits 2DLC can contribute to the efficiency of your analytical laboratory.   

 

Wednesday Free Vendor Technical Workshops

pre-register at sponsor's booth to attend


Wednesday, August 1, 2018 @ 12:25-1:25 PM

The New Benchmark for Preparative LC Workflows -  Pathways to Achieve Exceptional Accuracy and Flexibility
Sponsored by Agilent Technologies

Location: Harding Room (Mezzanine Level)

Speaker: Stefan Ullrich, Product Manager PREP Solutions, Agilent Technologies
Agilent offers high-efficiency InfinityLab LC and LC/MSD solutions ranging from analytical scale up to preparative scale for purification of multiple grams. Explore the portfolio of state-of-the-art LC purification instruments with scalable solutions that grow with your needs. Don’t miss a single compound through a wide range of fraction collectors and detectors including mass-selective detection.  Join the discussion and configure a comprehensive platform that meets your laboratory’s current and future needs.    

Wednesday, August 1, 2018 @ 12:25-1:25 PM

A Complete Solution for Streamlined LC Method Development

Sponsored by Waters Corporation

Location: Coolidge Room (Mezzanine Level)

Speaker: Margaret Maziarz, Principal Scientist, Waters Corporation

Method development is often a time-consuming process that is repeated many times throughout the lifecycle of a method. In order to maximize the understanding of a methods capabilities and robustness, a systematic screening protocol that employs a number of selectivity factors provides a thorough approach that ensures a greater chance of successful method validation and transfer in downstream processes. This workshop describes a synergistic approach towards method development that leverages the ACQUITY UPLC H-Class PLUS, sub-2-µm column chemistry, mass detection and Empower 3 Software to quickly develop robust methods.    

Wednesday, August 1, 2018 @ 12:25-1:25 PM

Orthogonal LC and LC-MS Methods for the Characterization of Size, Charge Variants and Glycoforms in Therapeutic Proteins

Sponsored by Phenomenex

Location: Hoover Room (Mezzanine Level)

Speaker: Carl Sanchez, Senior Research Scientist, Phenomenex

Determination of relative abundance of glycoforms is a critical quality attribute for monoclonal antibodies, since different glycosylation patterns affect important characteristics including effector function, pharmacokinetics, clearance, and immunogenicity. There are several methods to characterize and quantitate relative abundance of glycoforms. In this presentation, we will give an overview of LC related methods, including intact mass by LC-MS with high resolution Q-TOF, HILIC LC-MS of glycopeptides, and HILIC of N-linked glycans. We will discuss the strengths and limitations of each technique.  Also, novel HPLC columns based on advanced particle morphology and surface modification developed specifically for such analyses will be highlighted.